This page is maintained by EOD editors. The protocol is compiled from public sources; Michael Joyner hasn't taken it over yet.
Are you Michael Joyner? Claim this pagePhysician and physiologist at the Mayo Clinic, one of the world's leading authorities on the limits of human endurance and performance, with hundreds of papers on how the body responds to exercise and stress.
His research maps the physiological ceilings of human performance — VO2 max, oxygen delivery, and fatigue — and how the nervous system regulates blood pressure, heart rate, and metabolism under exercise, heat, and blood loss. He famously modeled the physiology of a sub-two-hour marathon years before it happened, and studies why trainability varies between people.
Know the limits to push them — human performance is governed by measurable physiology (oxygen delivery, cardiovascular function), and understanding those limits guides both elite performance and healthy aging.
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Finds by @michaeljoyner
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Community finds · the protocol
Submitted by members, independently of Michael Joyner.
BHB shot for evening clarity without the caffeine crash
Drinkable exogenous ketone (beta-hydroxybutyrate) in a 2.1 oz serving. Ketone-IQ claims ketones are 28% more efficient fuel than glucose for brain and muscle cells, though endurance data remains early-stage. The multiserving bottle lets you dose 1–3 shots daily. No sugar, no caffeine—useful for afternoon slumps or fasted work sessions if you want mental lift without stimulants.


WHOOP 5.0 membership tracks HRV-driven recovery, strain, and sleep—built for athletes who obsess over data
A wearable subscription that monitors heart rate variability (HRV), sleep quality, and training strain with a 14+ day battery. The Three tiers start at $199/yr for basic recovery tracking, up to $359/yr for medical-grade features like ECG and on-demand AFib detection. Includes lifetime warranty and 24/7 support. Women's hormonal insights and VO2 max zones are standard across all plans.


Pure creatine monohydrate, 5g daily, micronized for cognitive + physical performance
Momentous delivers 99.8% pure creatine monohydrate (Creapure®) in a 90-serving jar—the consensus research dose of 5g daily to support strength, endurance, and cognitive function. NSF Certified for Sport, micronized for easy mixing, with no additives. Most users notice subtle improvements within 1–2 weeks; full muscle saturation around 3–4 weeks.

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