Drinkable exogenous ketone (beta-hydroxybutyrate) in a 2.1 oz serving. Ketone-IQ claims ketones are 28% more efficient fuel than glucose for brain and muscle cells, though endurance data remains early-stage. The multiserving bottle lets you dose 1–3 shots daily. No sugar, no caffeine—useful for afternoon slumps or fasted work sessions if you want mental lift without stimulants.
Exogenous ketones reliably raise blood ketone levels and show promise in small RCTs for acute cognitive performance, endurance, and seizure reduction in epilepsy. However, human trial evidence remains sparse and inconsistent; most studies are small, short-term, or mechanistic. Long-term safety and whether chronic supplementation confers sustained metabolic or longevity benefits remain unproven.
Exogenous ketones (typically beta-hydroxybutyrate or ketone salts/esters) are ingested compounds that elevate blood ketone levels, mimicking the metabolic state of ketosis. They provide an alternative fuel source for the brain and muscles, potentially reducing reliance on glucose and increasing mitochondrial ATP (adenosine triphosphate) production while sparing muscle glycogen.
EOD publishes opinions and summaries of research about supplements, services, and protocols. It is not medical advice. Consult a qualified healthcare provider before changing your supplement, exercise, sleep, or medication regimen.
Some outbound links on EOD are affiliate links. If you buy through them we may earn a small commission, at no extra cost to you. It never influences what we publish or how it's ranked. Full disclosure.
EOD · 123 Placeholder Street, New York, NY 10001
May be an affiliate link.
Observational
“BACKGROUND: Exogenous ketone supplementation acutely elevates circulating beta-hydroxybutyrate (R-BHB), but the impact of chronic repeated dosing on exercise performance, cognition, mood, and cardiometabolic health remains unclear.”
“INTRODUCTION: Brain glucose metabolism declines and myelin deteriorates as Alzheimer's disease (AD) develops.”
“INTRODUCTION: Special Operations Forces (SOF) often conduct operations in physiologically stressful environments such as severe heat, cold, or hypoxia, which can induce decreases in a variety of cognitive abilities.”
“Very-low-carbohydrate diets (LCHF; <50 g/day) have been debated for their potential to lower pre-exercise muscle and liver glycogen stores and metabolic efficiency, risking premature fatigue.”
No large RCTs demonstrating durable improvements in weight loss, cognitive aging, or disease prevention. Acute nausea and GI distress are common. The endogenous ketogenic diet (via carbohydrate restriction) remains the gold standard for sustained ketosis; exogenous ketones do not replicate all metabolic effects of fasting or low-carb eating. Claims about 'brain fuel' and anti-aging lack human outcome data. Cost is high relative to evidence.
0 comments