Matt Kaeberlein
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Are you Matt Kaeberlein? Claim this pageGeroscientist, affiliate professor at the University of Washington and CEO of Optispan, and co-founder of the Dog Aging Project. One of the most visible researchers on rapamycin and the mTOR pathway as interventions in the biology of aging.
His work centers on the mTOR pathway and rapamycin, which extends lifespan across yeast, worms, flies, and mice; the Dog Aging Project extends this to tens of thousands of companion dogs — animals that share our environment and age-related diseases — including a trial of rapamycin on canine heart function and healthspan. He is also a vocal advocate for rigor and reproducibility in longevity research.
Translate geroscience from lab models to real lives — validate interventions like rapamycin in animals that age like we do, hold longevity claims to hard evidence, and measure healthspan, not just lifespan.
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Finds by @mattkaeberlein
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Community finds · the protocol
Submitted by members, independently of Matt Kaeberlein.
AgelessRx Metformin
Originally used to treat diabetes, it is now used off-label for longevity. Traditional doctors require high A1C or onset of diabetes. AgelessRx prescribes it for the longevity use-case. Prescription-strength, reviewed by licensed US prescriber, free medical evaluation provided.


160+ lab tests twice a year, tracked for life at $365
Function runs 160+ biomarkers annually (tested twice per year) across hormones, heart, metabolic, aging, and autoimmunity markers—including insulin, lipoproteins, hs-CRP, homocysteine, vitamin D, and heavy metals. Results are reviewed by clinicians and flagged for action. No insurance required, HSA/FSA eligible. The longevity crowd's baseline-tracking service.

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