Leonard Guarente
This page is maintained by EOD editors. The protocol is compiled from public sources; Leonard Guarente hasn't taken it over yet.
Are you Leonard Guarente? Claim this pageNovartis Professor of Biology at MIT and director of its Glenn Laboratory for the Science of Aging, and co-founder of Elysium Health. His discovery of the SIR2 gene launched the entire field of sirtuin biology.
He was first to identify SIR2 as a gene controlling aging in yeast and to show that sirtuins are NAD+-dependent enzymes — the original link between NAD+ and aging. His work established that the mammalian SIRT1 regulates metabolism and longevity, and that the age-related decline in NAD+ can be countered by precursor supplementation, the basis for Elysium's Basis.
Sirtuins are guardians of the genome powered by NAD+ — keep NAD+ levels youthful and you keep these repair-and-metabolism enzymes working, a strategy to slow the metabolic decline of aging.
@elysium (co-founded — NAD+ precursor and longevity supplements)
Finds by @leonardguarente
When @leonardguarente shares a find, it'll show up here.
Community finds · the protocol
Submitted by members, independently of Leonard Guarente.
The NR supplement actually backed by human trials—boosts NAD+ by over 50%
Tru Niagen's 300mg nicotinamide riboside (NR) is the NAD+ precursor with actual clinical data behind it. Chromadex's patented Niagen® form appears in 65% of registered NR trials. One capsule daily is clinically proven to increase NAD+ levels by over 50% in most people. It's designed for cellular repair and energy, though the mechanism is still being studied—not a magic anti-aging pill.

See something useful in @leonardguarente's feed? Members can save a find with a single tap.
Join EOD, freeEOD publishes opinions and summaries of research about supplements, services, and protocols. It is not medical advice. Consult a qualified healthcare provider before changing your supplement, exercise, sleep, or medication regimen.
Some outbound links on EOD are affiliate links. If you buy through them we may earn a small commission, at no extra cost to you. It never influences what we publish or how it's ranked. Full disclosure.
EOD · 123 Placeholder Street, New York, NY 10001

@LZ