Charles Brenner
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Are you Charles Brenner? Claim this pageBiochemist, the Alfred E. Mann Family Foundation Chair of Diabetes and Cancer Metabolism at City of Hope, and chief scientific advisor to the company behind Tru Niagen. He discovered a key vitamin route to NAD+ and is one of the most prominent — and most skeptical — voices in NAD science.
In 2004 he identified nicotinamide riboside (NR) as a vitamin precursor that cells convert to NAD+, and mapped the NR-kinase pathway. His lab built quantitative NAD-metabolomics to show how metabolic stress depletes the NAD system and how oral NR repletes it — the science behind the NR supplement Tru Niagen. He is also a public critic of overstated NAD and NMN claims.
Get the NAD science right — NAD+ falls under metabolic stress and can be restored with the right precursor, but the claims should track the actual human data, not the hype.
@truniagen (chief scientific advisor — its nicotinamide riboside is the NAD+ precursor he discovered)
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The NR supplement actually backed by human trials—boosts NAD+ by over 50%
Tru Niagen's 300mg nicotinamide riboside (NR) is the NAD+ precursor with actual clinical data behind it. Chromadex's patented Niagen® form appears in 65% of registered NR trials. One capsule daily is clinically proven to increase NAD+ levels by over 50% in most people. It's designed for cellular repair and energy, though the mechanism is still being studied—not a magic anti-aging pill.


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