Melatonin (2mg), L-theanine (200mg), and affron® saffron extract (28mg) in easy-to-swallow capsules. Start with one 30–60 minutes before bed; users report better sleep quality and wake-time clarity without the drowsy feeling some sleep aids cause. Gluten-free, vegetarian, vegan.
Multiple meta-analyses and RCTs show melatonin reduces sleep-onset latency and improves sleep quality in people with insomnia and circadian rhythm disorders. The effect is modest but consistent, with strongest evidence in shift workers and jet lag. Mechanism is well-established.
Melatonin is a hormone produced by the pineal gland that regulates circadian rhythm and sleep-wake cycles by binding to melatonin receptors (MT1 and MT2) in the suprachiasmatic nucleus and other tissues. It also acts as a free-radical scavenger and anti-inflammatory agent.
Meta-analysis
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“BACKGROUND: Behavioural, cognitive, and pharmacological interventions can all be effective for insomnia.”
“Previous studies have reported inconsistent results about exogenous melatonin's sleep-promoting effects.”
“BACKGROUND: Pharmacological treatment is common in practice and widely used for the management of insomnia.”
“Sleep disorders are frequent and can have serious consequences on patients' health and quality of life.”
Efficacy varies widely by dose, timing, and individual; most studies use 0.5–10 mg, but optimal dosing remains unclear. Long-term safety data beyond a few years is sparse. Melatonin does not reliably improve sleep maintenance (staying asleep) as much as sleep onset. Some trials show minimal benefit in primary insomnia compared to placebo, and publication bias may inflate effect sizes. Tolerance may develop with chronic use.
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