Orgain's unflavored colostrum powder (4.2 oz) mixes easily into cold drinks or yogurt. Contains immunoglobulins and growth factors to support immune and digestive health; sourced only after calves receive their first milk. Non-GMO, no added sugar or artificial ingredients.
Bovine colostrum shows consistent observational support for reducing gastrointestinal infection risk and improving intestinal permeability markers in small RCTs, particularly in athletes and people with compromised gut barriers. However, human trials remain limited in size and scope, and claims about systemic immune enhancement or athletic performance lack robust evidence. The strongest data concern gut-barrier integrity rather than broad health claims.
Colostrum is the nutrient-dense fluid secreted by mammals in the first few days after birth, rich in immunoglobulins (particularly IgA), lactoferrin, growth factors (IGF-1, EGF), and antimicrobial peptides. These components are proposed to support intestinal barrier function, modulate immune response, and promote tissue repair when consumed as a supplement.
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Observational
“Colostrum is the first milk produced by mammals for their young ones.”
“Colostrum supplementation has been confirmed to protect from upper respiratory tract infections (URTIs) in athletes.”
“BACKGROUND: Haemolytic uraemic syndrome (HUS) is a common cause of acquired kidney failure in children and rarely in adults.”
“BACKGROUND: Bovine colostrum (BC) contains a myriad of bioactive molecules that are renowned for possessing unique medicinal benefits in children and adults, and BC supplements are considered safe and cost-effective options to manage/preven”
Most RCTs are small (N < 100) and many are industry-sponsored. Evidence for athletic performance gains is mixed and inconsistent across studies. Bioavailability of intact growth factors (IGF-1, EGF) after oral ingestion is uncertain—stomach acid and proteolysis may degrade them before absorption. No long-term safety or efficacy data exist. Claims about immune system 'boosting' in healthy populations lack human trial support.
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